This post originated as a comment on a post in Toronto Mike’s blog post on the same topic.
Phone : currently rings the same for all callers – guitar solo from Deep Purple’s ‘Sometime I feel like screaming’
Email : both Gmail and Hotmail ids have different alerts so I know which is which.
SMS/MMS : has a bell like alert
Twitter, Facebook, Gmail and BBM alerts are unique dings so I know which is which.
I have my profile settings for sounds and alter with Vibrations+sound for only when my phone is in its holster.
What are your settings dear reader?